With funding from the National Institutes of Health, the study, which included more than 300,000 adults with Type 2 diabetes, produced results that suggest use of glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, and sodium-glucose cotransporter-2 inhibitors, or SGLT2 inhibitors, were associated with a significant reduction in risk of Alzheimers disease and related dementias compared with use of older medications, such as sulfonylureas or DPP4 inhibitors
Amylin analogs like cagrilintide appear to act via hindbrain satiety circuits and may also influence reward-related pathways involving AgRP and POMC neurons
The broader context of tissue repair peptides and healing applications through injury healing protocols provides additional perspective on how peptides can support recovery from the tissue damage that lupus causes
What began as a way to regulate insulin secretion is now evolving into a comprehensive metabolic strategy , addressing not just blood sugar control but also weight loss and overall metabolic health
2018;62:e01019-e1118
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